| Vice President | Calvin Coolidge (1921–1923) | |
|---|---|---|
| Secretary of State | Charles Evans Hughes (1921–1923) | |
| Secretary of the Treasury | Andrew W. Mellon (1921–1923) | |
| Secretary of War | John W. Weeks (1921–1923) | |
| Attorney General | Harry M. Daugherty (1921–1923) | |
| Postmaster General | ||
| Secretary of the Navy | Edwin Denby (1921–1923) | |
| Secretary of the Interior | Albert B. Fall (1921–1923) • Hubert Work (1923) | |
| Secretary of Agriculture | Henry Cantwell Wallace (1921–1923) | |
| Secretary of Commerce | Herbert Hoover (1921–1923) | |
| Secretary of Labor | James J. Davis (1921–1923) | |